Author(s):
Sharwari K. Sonawane, Yogesh P. Sharma, Sunil K. Mahajan
Email(s):
sharwarisonawane2808@gmail.com
DOI:
10.52711/2231-5659.2026.00041 
Address:
Sharwari K. Sonawane1*, Yogesh P. Sharma1, Sunil K. Mahajan2
1Department of Pharmaceutics, SSS’s Divine College Pharmacy, Nampur Road, Satana, Nashik, Maharashtra, India - 423301.
2Department of Chemistry, SSS’s Divine College Pharmacy, Nampur Road, Satana, Nashik, Maharashtra, India - 423301.
*Corresponding Author
Published In:
Volume - 16,
Issue - 3,
Year - 2026
ABSTRACT:
Stimuli-responsive hydrogels are a special type of smart material that can change their behavior when triggered by certain conditions, either inside the body or from outside sources. These changes might include swelling, breaking down, or shifting between liquid and gel forms. They react to things like changes in pH, body temperature, enzymes, light, magnetic or electric fields, and ultrasound. The way these hydrogels are made including the type of polymer and how it’s connected affects important features like how easily they break down, how much water they absorb, how porous they are, and how they release drugs. Depending on what triggers them, these hydrogels can be divided into different types, each with its own way of working and medical use. To make them work well for delivering medicine, they need to be carefully designed to match the drug, be safe for the body, respond well to the trigger, and stay strong enough during use. These smart materials have shown great promise in treating cancer, inflammation, brain diseases, eye problems, and even in tissue repair. Newer technologies like hydrogels that respond to more than one trigger, self-repairing gels, 3D and 4D printing, and those combined with sensors have made these systems even more useful. Still, there are some difficulties, such as making sure they work well inside the body, can be produced on a large scale, remain stable over time, and meet safety regulations. In the future, combining these hydrogels with personalized medicine and real-time monitoring could lead to more advanced and flexible ways to deliver drugs.
Cite this article:
Sharwari K. Sonawane, Yogesh P. Sharma, Sunil K. Mahajan. Stimuli Responsive Hydrogels: Smart Formulation Platforms for Pharmacological Targeting. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(3):278-6. doi: 10.52711/2231-5659.2026.00041
Cite(Electronic):
Sharwari K. Sonawane, Yogesh P. Sharma, Sunil K. Mahajan. Stimuli Responsive Hydrogels: Smart Formulation Platforms for Pharmacological Targeting. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(3):278-6. doi: 10.52711/2231-5659.2026.00041 Available on: https://www.ajpsonline.com/AbstractView.aspx?PID=2026-16-3-10
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