Author(s): Surabhi. S.M, Pinki Verma

Email(s): vermapinki05@gmail.com

DOI: 10.52711/2231-5659.2026.00009   

Address: Surabhi. S.M1, Pinki Verma2*
1Research Scholar, Department of Pharmacology, Aditya Bangalore Institute of Pharmacy Education and Research, Rajiv Gandhi University of Health Sciences, Yelahanka, Bengaluru, Karnataka, India.
2Associate Professor, Department of Pharmacology, Aditya Bangalore Institute of Pharmacy Education and Research, Rajiv Gandhi University of Health Sciences, Yelahanka, Bengaluru, Karnataka, India.
*Corresponding Author

Published In:   Volume - 16,      Issue - 1,     Year - 2026


ABSTRACT:
Hopea parviflora Bedd, belonging to the Dipterocarpaceae family, is a relatively underexplored medicinal species indigenous to the Indian subcontinent. Traditionally employed in folk medicine, this plant has recently garnered attention for its wide range of pharmacological activities. The present review consolidates and critically evaluates the available scientific literature on the phytochemical composition and therapeutic potential of H. parviflora, with a focus on its antioxidant, anti-inflammatory, antimicrobial, antidiabetic, and wound-healing properties. Rich in biologically active compounds including flavonoids, polyphenols, terpenoids, and tannins, the plant demonstrates multiple pharmacodynamic actions. Experimental studies conducted both in vitro and in vivo suggest that H. parviflora holds promise in the management of oxidative stress and metabolic disorders. However, current research is still in its early stages, and comprehensive preclinical and clinical studies are warranted to substantiate its medicinal value. This review seeks to establish a solid platform for future investigations and to support the advancement of H. parviflora as a viable candidate in phytopharmaceutical development. While initial experimental findings are encouraging, there remains a critical need for detailed clinical studies and mechanistic research to confirm the therapeutic efficacy and safety of Hopea parviflora. By offering an integrative overview of its phytochemical and pharmacological attributes, this review underscores the plant’s potential as a versatile resource for developing new plant-based therapeutic agents.


Cite this article:
Surabhi. S.M, Pinki Verma. A Comprehensive Review on the Bioactive Potential of Hopea parviflora in Modern Medicine. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(1):53-8. doi: 10.52711/2231-5659.2026.00009

Cite(Electronic):
Surabhi. S.M, Pinki Verma. A Comprehensive Review on the Bioactive Potential of Hopea parviflora in Modern Medicine. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(1):53-8. doi: 10.52711/2231-5659.2026.00009   Available on: https://www.ajpsonline.com/AbstractView.aspx?PID=2026-16-1-9


10. REFERENCES:
1.    WHO (2013). Traditional Medicine Strategy 2014–2023. World Health Organization.
2.    Nisha, K., Kumar, S., and Mani, V. Ethnobotanical relevance of Hopea parviflora in the Western Ghats. Indian Journal of Traditional Knowledge. 2019; 18(4): 678–683.
3.    U. Anand, N. Jacobo-Herrera, A. Altemimi, N. Lakhssassi.A comprehensive review on medicinal plants as antimicrobial therapeutics: potential avenues of biocompatible drug discovery Metabolites, Asian J. Pharm. Clin.  2019; 9:11
4.    Anand, R., Suresh, B., and Mahesh, P. Evaluation of antidiabetic properties of Hopea parviflora in experimental rat models. Journal of Applied Pharmaceutical Science. 2021; 11(3): 101–106.DOI: 10.1016/j.procbio.2019.10.025
5.    Thomas, M., and Joseph, A. Antibacterial and cytoprotective effects of Hopea parviflora leaf extract. Biomedical and Pharmacology Journal. 2022; 15(1):89–95.
6.    Beddome, R.H. Flora Sylvatica for Southern India. Madras: Gantz Brothers. 1869
7.    Gamble, J.S. Flora of the Presidency of Madras. London: Authority of the Secretary of State for India.1915–1935
8.    E.I. Buzas, The roles of extracellular vesicles in the immune system Nat Rev Immunol, Asian J. Pharm. Clin. Res. 2023; 23(4):  236-250
9.    Krishnaveni, M., Mirunalini, S. Therapeutic potential of Hopea parviflora against oxidative stress-induced diseases. Asian Journal of Pharmaceutical and Clinical Research. 2011; 4(3): 62–65.
10.    Council of Scientific and Industrial Research (CSIR). The Wealth of India: A Dictionary of Indian Raw Materials and Industrial Products, Vol. 5. New Delhi: CSIR.2003
11.    Harborne, J. B. Phytochemical Methods: A Guide to Modern Techniques of Plant Analysis. Springer.1998DOI: 10.1007/978-94-009-5955-3
12.    Prasad, M. N. V. Environmental Bioremediation Technologies. Springer.2008 DOI: 10.1007/978-3-540-34793-4
13.    Krishnaveni, M., and Mirunalini, S. Asian J. Pharm. Clin. Res.2011; 4(3): 62–65.
14.    Sanguni G, Thilaga G, Paustinaancy R, Gowri MAntioxidant Activity of Isatin-Schiff Base Scaffold: A Review. Asian J. Pharm. Clin. Res. 2025; 1(3). DOI: 10.52711/2231-5691.2025.00045
15.    A. Braca, N.D. Tommasi, L.D. Bari, et al. Antioxidant principles from Bauhinia tetrapotensis. Asian Journal of Pharmaceutical Sciences J Nat Prod. 2001; 64: 892-895
16.    J.M. Dennis, P.K Witting. Protective role for antioxidants in acute kidney disease Nutrients. Asian Journal of Pharmaceutical Science. 2017; 9(7). 
17.    Karthikeyan, M., et al. Subacute toxicity study of Hopea parviflora bark extract in rats. International Journal of Toxicological Sciences. 2018: 13(2): 87-94.
18.    S. Tomoo, Y. Keizo. History of antimicrobial agents and resistant bacteria Japan Med Assoc Asian J. Pharm. Clin. Res. 2009; 52(2): 103-108
19.    Vasanthi, H. R., et al. Evaluation of cytotoxic and antioxidant activity of Hopea parviflora extracts on human cancer cell lines. Pharmacognosy Journal. 2017; 9(6): 847-853. DOI: 10.5530/pj.2017.6.132
20.    Rajendran, R., et al. Antioxidant activity of Hopea parviflora leaf extracts in vitro. Journal of Pharmacy Research. 2017; 11(5): 452-456.
21.    Ravichandran, M., et al. Polyherbal antidiabetic formulations incorporating Hopea parviflora: A preclinical evaluation. Journal of Ethnopharmacology. 2011; 265: 113280.DOI: 10.1016/j.jep.2020.113280
22.    M. Pagac, J. Hajnys, Q.P. Ma, L. Jancar, J. Jansa, P. Stefek, et al. A review of vat photopolymerization technology: materials, applications, challenges, and future trends of 3D printing Polymers Asian J. Pharm. Clin. 2021; 13: 1-20
23.    Hiral A. Makadia, Ami Y. Bhatt, Ramesh B. Parmar, Jalpa S. Paun, H. M. Tank. Self-nano Emulsifying Drug Delivery System (SNEDDS): Future Aspects. Asian J. Pharm. Clin. Res. 2013, 3(1).
24.    A.A. Khalil, A. Abou Gabal, A.A. Abdellatif, et al. Protective role of probiotic lactic acid bacteria against dietary fumonisin B1-induced toxicity and DNA-fragmentation in Sprague-Dawley ratsPrep Biochem Biotechnol. Asian J. Pharm. Clin. 2015; 45: 530-550
25.    Selvaraj, K., et al. HPLC-based standardization and development of Hopea parviflora phytopharmaceuticals. Indian Journal of Natural Products and Resources. 2020; 11(3): 162-167.
26.    Manickam, A., et al. Development of functional food formulations using Hopea parviflora for diabetic patients. Food Science Research Journal. 2019; 10(2): 178-184.
27.    S. Dewanjee, J. Vallamkondu, R.S. Kalra, A. John, P.H. Reddy, R. Kandimalla. Autophagy in the diabetic heart: a potential pharmacotherapeutic target in diabetic cardiomyopathyAgeing Res Rev, Asian J. Pharm. Clin. 2021; 68: Article 101338
28.    Menon, R., et al. Observational study on the effect of a polyherbal formulation containing Hopea parviflora in diabetic patients. AYUSH Clinical Bulletin. 2020; 12(2): 29–33.
29.    Anitha, P., et al. Assessment of safety and tolerability of Hopea parviflora extract capsules in healthy volunteers: A preliminary report. Indian Journal of Traditional Knowledge. 2021; 20(4): 900–904.
30.    Nair, R., Kalariya, T., Sumitra, C. Antibacterial activity of some selected Indian medicinal flora. Turkish Journal of Biology. 2011; 29: 41–47.
31.    Sasidharan, S., Chen, Y., Saravanan, D., Sundram, K. M., Yoga Latha, L. Extraction, isolation and characterization of bioactive compounds from plants’ extracts. African Journal of Traditional, Complementary and Alternative Medicines. 2020; 8(1): 1–10.DOI: 10.4314/ajtcam.v8i1.60483
32.    Kumar, A. R., and Mohan, V. R. Conservation concerns of endemic and threatened medicinal plants. Journal of Biodiversity and Endangered Species. 2018; 6(1): 1–6.
33.    Patra, J. K., Das, G., Fraceto, L. F., Campos, E. V., Rodriguez-Torres, M. P., Acosta-Torres, L. S., and Shin, H. S. Nano based drug delivery systems: Recent developments and future prospects. Journal of Nanobiotechnology. 2021; 19(1): 1–33. DOI: 10.1186/s12951-021-00826-6


Recomonded Articles:

Author(s): Sarika V. Khandbahale, Kanchan R. Pagar, Rupali. V. Khankari

DOI: 10.5958/2231-5659.2019.00018.3         Access: Open Access Read More

Author(s): Mohd. Yaqub Khan, Maryada Roy, Brijesh Kumar Saroj, Sudhakar Dubey, Vineet Kumar Sharma

DOI: 10.5958/2231-5659.2015.00019.3         Access: Open Access Read More

Author(s): Mukesh Sharma, Kushagra Nagori, Shubhang Agrawal, Vinay S. Verma, Hemendra Swarnakar, Sanjay Vaishnav, Md. Nazir, Nasim Khan, Ajay Singh

DOI:         Access: Open Access Read More

Author(s): K.Vijaya Sri, Guda Santhoshini, D. Ravi Sankar, K.Niharika

DOI: 10.5958/2231-5659.2018.00005.X         Access: Open Access Read More

Author(s): Yogita V. Dalvi

DOI: 10.5958/2231-5659.2018.00025.5         Access: Open Access Read More

Author(s): Niraj Kale, Sanket Rathod, Snehal More, Namdeo Shinde

DOI: 10.52711/2231-5659.2021.00047         Access: Open Access Read More

Author(s): Anubhav Dubey, Yatendra Singh

DOI: 10.52711/2231-5659.2021.00036         Access: Open Access Read More

Author(s): S. S. Shuka, Bina Gidwani, R. Pandey, S. P. Rao, V. Singh, Amber Vyas

DOI:         Access: Open Access Read More

Author(s): Rahul Jodh, Mukund Tawar, Aparna Kachewar, Vishal Mahanur, Yash Sureka, Virendra Atole

DOI: 10.52711/2231-5659.2022.00006         Access: Open Access Read More

Author(s): Omkar A. Devade, Rohan D. Londhe, Nisarga V. Sokate, Utkarsha R. Randave, Pallavi A. Ranpise

DOI: 10.52711/2231-5659.2022.00039         Access: Open Access Read More

Author(s): Akshay R. Yadav, Shrinivas K. Mohite, Chandrakant S. Magdum

DOI: 10.5958/2231-5659.2020.00028.4         Access: Open Access Read More

Author(s): Pratibha Gavarkar, Pramod Patil, Akshay Sutar, Shridhar Rasal, Dyaneshwar Surwase

DOI: 10.5958/2231-5659.2016.00029.1         Access: Open Access Read More

Author(s): Santosh B. Dighe, Dnyanda H. Kangude, Dnyaneshwari B. Kangune, Akanksha S. Tambe

DOI: 10.52711/2231-5659.2023.00052         Access: Open Access Read More

Author(s): Sunity Singh, Himanshu Joshi

DOI:         Access: Open Access Read More

Author(s): Yogita Chowdhary

DOI: 10.52711/2231-5659.2021.00044         Access: Open Access Read More

Author(s): Ashwini S. Jadhav, Omkar A. Patil, Sampada V. Kadam, Dr. Mangesh A. Bhutkar

DOI: 10.5958/2231-5659.2020.00006.5         Access: Open Access Read More

Author(s): Goli.Venkateshwarlu, Ragya Eslavath, Santhosh. Anasuri, Gutha.Suma, Kasireddy.Swapna, E.Rajeshwari

DOI:         Access: Open Access Read More

Author(s): Srikanth Jupudi, Padmini K., Jaya Preethi P., Deepak Bharadwaj P.V.P., Vengal Rao P.

DOI:         Access: Open Access Read More

Asian Journal of Research in Pharmaceutical Sciences (AJPSci) is an international, peer-reviewed journal, devoted to pharmaceutical sciences....... Read more >>>

RNI: Not Available                     
DOI: 10.52711/2231-5659 

Journal Policies & Information



Recent Articles




Tags