Author(s):
Iftesam Samir Momin, Sayali Suresh Patil, Amruta Zakas Patil, Vaishnavi Pandurang Khot, Gayatri Vijay Farakate, Dhanraj Raghunathrao Jadge, Shalini Ashok Shinde, Aniket Chandrakant Thanekar
Email(s):
ms.shalinishinde177@gmail.com , athanekar01@gmail.com
DOI:
10.52711/2231-5659.2026.00049 
Address:
Iftesam Samir Momin1, Sayali Suresh Patil2, Amruta Zakas Patil3, Vaishnavi Pandurang Khot4, Gayatri Vijay Farakate5, Dhanraj Raghunathrao Jadge6, Shalini Ashok Shinde7, Aniket Chandrakant Thanekar8*
Department of Pharmaceutical Chemistry, Womens College of Pharmacy, Peth-Vadgaon 416112, India.
1ORCIDs: 0009-0001-2873-3180, 2ORCIDs: 0009-0003-4475-3004,3ORCIDs: 0009-0008-5228-5251,
4ORCIDs: 0009-0008-5462-0551, 5ORCIDs: 0009-0002-9402-8719,6ORCIDs: 0000-0003-3979-1682,
7ORCIDs: 0009-0001-8322-5007, 8ORCIDs: 0009-0003-3806-0017
*Corresponding Author
Published In:
Volume - 16,
Issue - 4,
Year - 2026
ABSTRACT:
The creation of innovative medication delivery systems is a result of the increased interest in mixing synthetic and herbal medicines for improved therapeutic effects. This study aims to develop and assess a topical emulgel for wound healing and anti-inflammatory applications that combines neem oil, a traditional herbal treatment, with aspirin, a well-known NSAID. In addition to specific emulsifiers, humectants, and penetration enhancers, Carbopol 930 was used as a gelling agent in the formulation's preparation. The F1 formulation outperformed the other two batches in terms of physicochemical properties, such as pH, viscosity, spreadability, and extrudability. Studies on in vitro permeation showed a biphasic drug release profile, with the highest absorption occurring after three hours. Significant antibacterial efficacy against Escherichia coli was demonstrated by the formulation, along with thermal stability, with a maximum inhibition zone. These findings imply that the aspirin-neem oil emulgel combines the advantages of synthetic and herbal pharmacotherapy to provide a promising dual-action therapeutic alternative for localized inflammation and infection control.
Cite this article:
Iftesam Samir Momin, Sayali Suresh Patil, Amruta Zakas Patil, Vaishnavi Pandurang Khot, Gayatri Vijay Farakate, Dhanraj Raghunathrao Jadge, Shalini Ashok Shinde, Aniket Chandrakant Thanekar. Development and Evaluation of Aspirin-Neem oil based Emulgel for Wound Healing. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(4):333-8. doi: 10.52711/2231-5659.2026.00049
Cite(Electronic):
Iftesam Samir Momin, Sayali Suresh Patil, Amruta Zakas Patil, Vaishnavi Pandurang Khot, Gayatri Vijay Farakate, Dhanraj Raghunathrao Jadge, Shalini Ashok Shinde, Aniket Chandrakant Thanekar. Development and Evaluation of Aspirin-Neem oil based Emulgel for Wound Healing. Asian Journal of Research in Pharmaceutical Sciences. 2026; 16(4):333-8. doi: 10.52711/2231-5659.2026.00049 Available on: https://www.ajpsonline.com/AbstractView.aspx?PID=2026-16-4-2
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